1991-1995
1991
Siebendritt, R., Sharma, A.K., Rudolph, R. & Jaenicke, R. (1991)
Biol. Chem. Hoppe-Seyler 372, 23-26
Analysis of Protein Folding by FPLC: Modular Domain Folding of II-Crystallin from Calf Eye Lens.
Buchner, J. & Rudolph, R. (1991)
Bio/Technology 9, 157-162
Renaturation, Purification and Characterization of Recombinant Fab-Fragments Produced in Escherichia coli.
Buchner, J., Schmidt, M., Fuchs, M., Jaenicke, R., Rudolph, R., Schmid, F.X. & Kiefhaber, T. (1991)
Biochemistry 30, 1586-1591
GroE Facilitates Refolding of Citrate Synthase by Suppressing Aggregation.
Goldberg, M.E., Rudolph, R. & Jaenicke, R. (1991)
Biochemistry 30, 2790-2797
A Kinetic Study of the Competition Between Renaturation and Aggregation During the Refolding of Denatured-Reduced Egg White Lysozyme.
Martin, U., Fischer, S., Kohnert, U., Opitz, U., Rudolph, R., Sponer, G., Stern, A. & Strein, K. (1991)
Thrombosis and Haemostasis 65, 560-564
Thrombolysis with an Escherichia coli Produced Recombinant Plasminogen Activator (BM 06.022) in a Rabbit Model of Jugular Vein Thrombosis.
Martin, U., Fischer, S., Kohnert, U., Rudolph, R., Sponer, G., Stern, A. & Strein, K. (1991)
Thrombosis Research 62, 137-146
Pharmacokinetic Properties of an Escherichia coli - Produced Recombinant Plasminogen Activator (BM 06.022) in Rabbits.
Buchner, J., Renner, M., Lilie, H., Hinz, H.-J., Jaenicke, R., Kiefhaber, T. & Rudolph, R. (1991)
Biochemistry 30, 6922 - 6929
Alternatively Folded States of an Immunoglobulin.
Buchner, J. & Rudolph, R. (1991)
Current Opinion in Biotechnology 2, 532-538
Routes to Active Proteins from Transformed Microorganisms.
Kiefhaber, T., Rudolph, R., Kohler, H.-H. & Buchner, J. (1991)
Bio/Technology 9, 825-829
Protein Aggregation in vitro and in vivo: A Quantitative Model of the Kinetic Competition Between Folding and Aggregation.
Martin, U., Fischer, S., Kohnert, U., Rudolph, R., Sponer, G., Stern, A. & Strein, K. (1991)
J. Cardiovascular Pharmacol. 18, 111-119
Coronary Thrombolytic Properties of a Novel Recombinant Plasminogen Activator (BM 06.022) in a Canine Model.
Höll-Neugebauer, B., Rudolph, R., Schmidt, M. & Buchner, J. (1991)
Biochemistry 30, 11609-11614
Reconstitution of a Heat Shock Effect in in vitro: Influence of GroE on the Thermal Aggregation of -Glucosidase from Yeast.
1992
Kohnert, U., Rudolph, R., Verheijen, J.H., Weening-Verhoeff, E.J.D., Stern, A., Opitz, U., Martin, U., Lill, H., Prinz, H., Lechner, M., Kresse, G.-B., Buckel, P. & Fischer, S. (1992)
Protein Engineering 5, 93-100
Biochemical Properties of the Kringle 2 and Protease Domains are Maintained in the Refolded t-PA Deletion Variant BM 06.022.
Rudolph, R., Opitz, U., Hesse, F., Rießland, R. & Fischer, S. (1992)
Biotechnology International (North, K., ed.) pp. 321-325, Century Press Ltd., London
Reactivation of Microbially Produced Human Tissue-Type Plasminogen Activator.
Rudolph, R., Siebendritt, R. & Kiefhaber, T. (1992)
Protein Science 1, 654-666
Reversible Unfolding and Refolding Behavior of a Monomeric Aldolase from Staphylococcus aureus.
Rudolph, R. (1992)
Harnessing Biotechnology for the 21st Century (Ladisch, M.R. & Bose, A., eds.) pp. 295-297, American Chemical Society, Washington
Folding for Profit: Renaturation of Recombinant Proteins from Inclusion Bodies as a New Downstream Process.
Martin, U., Fischer, S., Kohnert, U., Opitz, U., Rudolph, R., Sponer, G., Stern, A. & Strein, K. (1992)
Arch. Pharmacol. 108-113
Pharmacokinetic and Thrombolytic Properties of Unglycosylated Recombinant Tissue-Type Plasminogen Activator (BM 06.021) Produced in Escherichia coli.
Stockinger, H., Kubbies, M., Rudolph, R., Stern, A., Kohnert, U. & Fischer, S. (1992)
Thrombosis Research 67, 589-599
Binding of Recombinant Variants of Human Tissue-Type Plasminogen Activator (t-PA) to Human Umbilical Vein Endothelial Cells.
Risse, B., Stempfer, G., Rudolph, R., Möllering, H. & Jaenicke, R. (1992)
Protein Science 1, 1699-1709
Stability and Reconstitution of Pyruvate Oxidase from Lactobacillus plantarum: Dissection of the Stabilizing Effects of Coenzyme Binding and Subunit Interaction.
Risse, B., Stempfer, G., Rudolph, R., Schumacher, G. & Jaenicke, R. (1992)
Protein Science 1, 1710-1718
Characterization of the Stabilizing Effect of Point Mutations of Pyruvate Oxidase from Lactobacillus plantarum: Protection of the Native State by Modulating Coenzyme Binding and Subunit Interaction.
Zink, T., Ross, A., Ambrosius, D., Rudolph, R. & Holak, T.A. (1992)
FEBS Letters 314, 435-439
Secondary Structure of Human Granulocyte Colony-Stimulating Factor Derived from NMR Spectroscopy.
1993
81. Stoyan, T., Michaelis, U., Schooltink, H., Van Dam, M., Rudolph, R., Heinrich, P.C. & Rose-John, S. (1993)
Eur. J. Biochem. 216, 239-245
Recombinant Soluble Human Interleukin-6 Receptor: Expression in Escherichia coli, Renaturation and Purification.
82. Lilie, H., Lang, K., Rudolph, R. & Buchner, J. (1993)
Protein Science 2, 1490-1496
Prolyl Isomerases Catalyze Antibody Folding in vitro.
83. Schumann, J., Böhm, G., Schumacher, G., Rudolph, R. & Jaenicke, R. (1993)
Protein Science 2, 1612-1620
Stabilization of Creatinase from Pseudomonas putida by Random Mutagenesis.
1994
Muller, Y.A., Schumacher, G., Rudolph, R. & Schulz, G.E. (1994)
J. Mol. Biol. 237, 315-335
The Refined Structures of a Stabilized Mutant and of Wild-type Pyruvate Oxidase from Lactobacillus plantarum.
Zink, T., Ross, A., Lüers, K., Cieslar, C., Rudolph, R. & Holak, T.A. (1994)
Biochemistry 33, 8453-8463
Structure and Dynamics of the Human Granulocyte Colony-Stimulating Factor Determined by NMR Spectroscopy. Loop Mobility in a Four-Helix-Bundle Protein.
1995
Lilie, H., Rudolph, R. & Buchner, J. (1995)
J. Mol. Biol. 248, 190-201
Association of Antibody Chains at Different Stages of Folding: Prolyl Isomerization Occurs after Formation of Quaternary Structure.